Article
[Studies on mechanism of carcinogenesis in vitro. IV. Studies on relationship between frequency of chromosome 15 monosomy and malignant expression of different clones from malignantly transformed baby hamster lung cells (BHL B4)].
Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae - 1 Apr 1990
Li S
Abstract excerpt
The proceeding of malignantly transformed rodent cells in vitro is often accompanied by regular variation of chromosome numbers and structures. In order to clarify the relationship between them, we obtained five clones C1-1-5-from BHL B4, cell line, and analysed their biological characteristics. Results showed a positive correlation between frequency of chromosome 15 monosomy, it is suggested that suppressive...
Topics
- Animals
- Cell Line, Transformed
- Cell Transformation, Neoplastic
- Chromosome Deletion
- Cricetinae
- Fibroblasts
- Gene Expression Regulation, Neoplastic
- Lung
- Mesocricetus
- Methylnitronitrosoguanidine