Article
Animal models of GWAS-identified type 2 diabetes genes.
Journal of diabetes research - 1 Jan 2013
da Silva Xavier Gabriela, Bellomo Elisa A, McGinty James A, French Paul M, Rutter Guy A
Abstract excerpt
More than 65 loci, encoding up to 500 different genes, have been implicated by genome-wide association studies (GWAS) as conferring an increased risk of developing type 2 diabetes (T2D). Whilst mouse models have in the past been central to understanding the mechanisms through which more penetrant...
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