Transgenic approaches to the pathogenesis of NIDDM.

doi:10.2337/diab.43.12.1394

Back to search

Article

Transgenic approaches to the pathogenesis of NIDDM.

Diabetes - 1 Dec 1994

Moller D E

Abstract excerpt

The pathogenesis of non-insulin-dependent diabetes mellitus (NIDDM) involves complex interactions between multiple physiological defects, both genetic and acquired. The application of transgenic technology to create animal models that address questions concerning NIDDM (and obesity) is a very rec...

Topics

Animals
Diabetes Mellitus, Experimental
Diabetes Mellitus, Type 2
Glucose
Humans
Insulin
Insulin Secretion
Liver
Mice
Mice, Transgenic
Mutation
Obesity

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.