Article
Polymorphisms but not mutations of the KCNQ1 gene are associated with lone atrial fibrillation in the Chinese Han population.
TheScientificWorldJournal - 1 Jan 2013
Chu Hui-min, Feng Ming-jun, Li Yi-gang, Zhang Yi-xin, Ma Ji-fang, He Bin, Yu Yi-bo, Liu Jing, Chen Xiao-min
Abstract excerpt
BACKGROUND: Recent studies suggest that mutation of the slow delayed rectifier potassium channel (IKs) contributes to familial atrial fibrillation (FAF). In the current study, we identified common genetic variants of KCNQ1 and explored the potential association between KCNQ1 polymorphism with lone AF (LAF). METHODS: Clinical data and blood samples were collected from 190 Han Chinese patients with sporadic AF and...
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