Article
Plasma YKL-40 and CHI3L1 in systemic inflammation and sepsis-experience from two prospective cohorts.
Immunobiology - 1 Oct 2013
Kornblit Brian, Hellemann Dorthe, Munthe-Fog Lea, Bonde Jan, Strøm Jens J, Madsen Hans O, Johansen Julia S, Garred Peter
Abstract excerpt
YKL-40, derived from the CHI3L1 gene, has been associated with outcome of infectious and inflammatory diseases. We hypothesized that plasma YKL-40 concentrations and CHI3L1 genotype could be used as prognostic biomarkers in the assessment of systemic inflammatory response syndrome (SIRS) and sepsis. The objective of the study was to assess the prognostic value of plasma YKL-40 and CHI3L1 genotype in patients with...
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