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Article

The 372 T/C genetic polymorphism of TIMP-1 is associated with serum levels of TIMP-1 and survival in patients with severe sepsis.

Critical care (London, England) - 25 May 2013

Lorente Leonardo, Martín Mar, Plasencia Fátima, Solé-Violán Jordi, Blanquer José, Labarta Lorenzo, Díaz César, Borreguero-León Juan María, Jiménez Alejandro, Páramo José Antonio, Orbe Josune, Rodríguez José A, Salido Eduardo

Abstract excerpt

INTRODUCTION: Previous studies have found higher circulating levels of tissue inhibitor of matrix metalloproteinase (TIMP)-1 in nonsurviving septic patients than in surviving septic patients, and an association between the 372 T/C genetic polymorphism of TIMP-1 and the risk of developing certain diseases. However, the relationship between genetic polymorphisms of TIMP-1, circulating TIMP-1 levels and survival in...

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Identifiers

PMID: 23706069
DOI: 10.1186/cc12739
PMCID: PMC3706773

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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