Article
Genome-wide association study of primary tooth eruption identifies pleiotropic loci associated with height and craniofacial distances.
Human molecular genetics - 15 Sept 2013
Fatemifar Ghazaleh, Hoggart Clive J, Paternoster Lavinia, Kemp John P, Prokopenko Inga, Horikoshi Momoko, Wright Victoria J, Tobias Jon H, Richmond Stephen, Zhurov Alexei I, Toma Arshed M, Pouta Anneli, Taanila Anja, Sipila Kirsi, Lähdesmäki Raija, Pillas Demetris, Geller Frank, Feenstra Bjarke, Melbye Mads, Nohr Ellen A, Ring Susan M, St Pourcain Beate, Timpson Nicholas J, Davey Smith George, Jarvelin Marjo-Riitta, Evans David M
Abstract excerpt
Twin and family studies indicate that the timing of primary tooth eruption is highly heritable, with estimates typically exceeding 80%. To identify variants involved in primary tooth eruption, we performed a population-based genome-wide association study of 'age at first tooth' and 'number of teeth' using 5998 and 6609 individuals, respectively, from the Avon Longitudinal Study of Parents and Children (ALSPAC)...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.