Article
Genome-wide association study identifies four loci associated with eruption of permanent teeth.
PLoS genetics - 1 Sept 2011
Geller Frank, Feenstra Bjarke, Zhang Hao, Shaffer John R, Hansen Thomas, Esserlind Ann-Louise, Boyd Heather A, Nohr Ellen A, Timpson Nicholas J, Fatemifar Ghazaleh, Paternoster Lavinia, Evans David M, Weyant Robert J, Levy Steven M, Lathrop Mark, Smith George Davey, Murray Jeffrey C, Olesen Jes, Werge Thomas, Marazita Mary L, Sørensen Thorkild I A, Melbye Mads
Abstract excerpt
The sequence and timing of permanent tooth eruption is thought to be highly heritable and can have important implications for the risk of malocclusion, crowding, and periodontal disease. We conducted a genome-wide association study of number of permanent teeth erupted between age 6 and 14 years, analyzed as age-adjusted standard deviation score averaged over multiple time points, based on childhood records for...
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