Article
Novel Genetic Determinants of Dental Maturation in Children.
Journal of dental research - 1 Mar 2023
Grgic O, Prijatelj V, Dudakovic A, Vucic S, Dhamo B, Trajanoska K, Monnereau C, Zrimsek M, Gautvik K M, Reppe S, Shimizu E, Haworth S, Timpson N J, Jaddoe V W V, Jarvelin M-R, Evans D, Uitterlinden A G, Ongkosuwito E M, van Wijnen A J, Medina-Gomez C, Rivadeneira F, Wolvius E B
Abstract excerpt
Dental occlusion requires harmonious development of teeth, jaws, and other elements of the craniofacial complex, which are regulated by environmental and genetic factors. We performed the first genome-wide association study (GWAS) on dental development (DD) using the Demirjian radiographic method. Radiographic assessments from participants of the Generation R Study (primary study population, N1 = 2,793; mean age...
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