Article
Genome-wide association study reveals multiple loci associated with primary tooth development during infancy.
PLoS genetics - 26 Feb 2010
Pillas Demetris, Hoggart Clive J, Evans David M, O'Reilly Paul F, Sipilä Kirsi, Lähdesmäki Raija, Millwood Iona Y, Kaakinen Marika, Netuveli Gopalakrishnan, Blane David, Charoen Pimphen, Sovio Ulla, Pouta Anneli, Freimer Nelson, Hartikainen Anna-Liisa, Laitinen Jaana, Vaara Sarianna, Glaser Beate, Crawford Peter, Timpson Nicholas J, Ring Susan M, Deng Guohong, Zhang Weihua, McCarthy Mark I, Deloukas Panos, Peltonen Leena, Elliott Paul, Coin Lachlan J M, Smith George Davey, Jarvelin Marjo-Riitta
Abstract excerpt
Tooth development is a highly heritable process which relates to other growth and developmental processes, and which interacts with the development of the entire craniofacial complex. Abnormalities of tooth development are common, with tooth agenesis being the most common developmental anomaly in humans. We performed a genome-wide association study of time to first tooth eruption and number of teeth at one year...
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