Article
Identification of intramural epithelial networks linked to peribiliary glands that express progenitor cell markers and proliferate after injury in mice.
Hepatology (Baltimore, Md.) - 1 Oct 2013
DiPaola Frank, Shivakumar Pranavkumar, Pfister Janet, Walters Stephanie, Sabla Gregg, Bezerra Jorge A
Abstract excerpt
UNLABELLED: Peribiliary glands (PBGs) are clusters of epithelial cells residing in the submucosal compartment of extrahepatic bile ducts (EHBDs). Though their function is largely undefined, they may represent a stem cell niche. Here, we hypothesized that PBGs are populated by mature and undifferentiated cells capable of proliferation in pathological states. To address this hypothesis, we developed a novel...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.