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Biliary tree stem/progenitor cells in glands of extrahepatic and intraheptic bile ducts: an anatomical in situ study yielding evidence of maturational lineages.

Journal of anatomy - 1 Feb 2012

Carpino Guido, Cardinale Vincenzo, Onori Paolo, Franchitto Antonio, Berloco Pasquale Bartolomeo, Rossi Massimo, Wang Yunfang, Semeraro Rossella, Anceschi Maurizio, Brunelli Roberto, Alvaro Domenico, Reid Lola M, Gaudio Eugenio

Abstract excerpt

Stem/progenitors have been identified intrahepatically in the canals of Hering and extrahepatically in glands of the biliary tree. Glands of the biliary tree (peribiliary glands) are tubulo-alveolar glands with mucinous and serous acini, located deep within intrahepatic and extrahepatic bile ducts. We have shown that biliary tree stem/progenitors (BTSCs) are multipotent, giving rise in vitro and in vivo to...

Topics

Adult Stem Cells
Bile Ducts, Extrahepatic
Bile Ducts, Intrahepatic
Biliary Tract
Biomarkers
Gallbladder
Humans
Immunohistochemistry
Liver

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Multipotent Stem Cells

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Identifiers

PMID: 22136171
DOI: 10.1111/j.1469-7580.2011.01462.x
PMCID: PMC3275774

Genes

PDX1
SOX17
CXCR4
SOX9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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