Article
Accumulation of the mutations in basal core promoter of hepatitis B virus subgenotype C1 increase the risk of hepatocellular carcinoma in Southern China.
International journal of clinical and experimental pathology - 1 Jan 2013
Li Weihua, Chen Guangyuan, Yu Xianwen, Shi Yongying, Peng Miaoguan, Wei Jianjun
Abstract excerpt
UNLABELLED: Hepatitis B virus (HBV) genotype C is associated with the development of hepatocellular carcinoma (HCC). In addition, HBV subgenotype C1 is the major subgenotype in Southern China. The aim of this study was to investigate whether there was the specific mutation patterns in HBV/C1 asso...
Topics
- Carcinoma, Hepatocellular
- Case-Control Studies
- Chi-Square Distribution
- China
- Cross-Sectional Studies
- Gene Frequency
- Genetic Predisposition to Disease
- Hep G2 Cells
- Hepatitis B
- Hepatitis B virus
- Humans
- Liver Neoplasms
- Mutation
- Phenotype