Article
Temporal acquisition of sequential mutations in the enhancer II and basal core promoter of HBV in individuals at high risk for hepatocellular carcinoma.
Carcinogenesis - 1 Jan 2011
Bai Xin, Zhu Yu, Jin Yan, Guo Xia, Qian Gengsun, Chen Taoyang, Zhang Jing, Wang Jinbing, Groopman John D, Gu Jianren, Tu Hong
Abstract excerpt
To investigate the roles of mutations in enhancer II (Enh II) and basal core promoter (BCP) of hepatitis B virus (HBV) in hepatocellular carcinoma (HCC), we determined the sequence of Enh II/BCP in 152 HCC and 136 non-HCC patients from a high-incidence area of East China. A longitudinal study was...
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