Article
Estrogen receptor 1 gene as a tumor suppressor gene in hepatocellular carcinoma detected by triple-combination array analysis.
International journal of oncology - 1 Jul 2013
Hishida Mitsuhiro, Nomoto Shuji, Inokawa Yoshikuni, Hayashi Masamichi, Kanda Mitsuro, Okamura Yukiyasu, Nishikawa Yoko, Tanaka Chie, Kobayashi Daisuke, Yamada Suguru, Nakayama Goro, Fujii Tsutomu, Sugimoto Hiroyuki, Koike Masahiko, Fujiwara Michitaka, Takeda Shin, Kodera Yasuhiro
Abstract excerpt
Hepatocellular carcinoma (HCC) is one of the top five causes of cancer-related deaths worldwide. Recent developments in the treatment of HCC remain insufficient to cure unresectable disease or to prevent HCC. Consistent efforts are, therefore, needed to deepen understanding of pathogenesis of the disease. Genome-wide gene expression profile analyses can now detect various candidate genes that are modified by HCC....
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