Article
Epidermal growth factor-containing fibulin-like extracellular matrix protein 1, EFEMP1, a novel tumor-suppressor gene detected in hepatocellular carcinoma using double combination array analysis.
Annals of surgical oncology - 1 Mar 2010
Nomoto Shuji, Kanda Mitsuro, Okamura Yukiyasu, Nishikawa Yoko, Qiyong Li, Fujii Tsutomu, Sugimoto Hiroyuki, Takeda Shin, Nakao Akimasa
Abstract excerpt
BACKGROUND: Although hepatocellular carcinoma (HCC) is one of the commonest cancers worldwide, the underlying molecular mechanisms contributing to hepatocarcinogenesis are still not clear. METHODS: In this study, we performed double array analysis, consisting of both expression profiling and karyotyping analysis using single-nucleotide polymorphism (SNP) array, of the same HCC sample from a 68-year-old woman with...
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