Article
Detection of metallothionein 1G as a methylated tumor suppressor gene in human hepatocellular carcinoma using a novel method of double combination array analysis.
International journal of oncology - 1 Sept 2009
Kanda Mitsuro, Nomoto Shuji, Okamura Yukiyasu, Nishikawa Yoko, Sugimoto Hiroyuki, Kanazumi Naohito, Takeda Shin, Nakao Akimasa
Abstract excerpt
Gene expression profiling or karyotyping analysis has made it possible to identify novel genes with altered expressions or copy numbers that have not been previously reported in liver cancer. On the same HCC sample, we performed double array analysis, both expression profiling and karyotyping analysis using a single nucleotide polymorphism (SNP) array in an attempt to find a novel tumor suppressor gene for its...
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