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Article

Phenotypical analysis of atypical PKCs in vivo function display a compensatory system at mouse embryonic day 7.5.

PloS one - 1 Jan 2013

Seidl Sebastian, Braun Ursula, Roos Norbert, Li Shaohua, Lüdtke Timo H-W, Kispert Andreas, Leitges Michael

Abstract excerpt

BACKGROUND: The atypical protein kinases C (PKC) isoforms ι/λ and ζ play crucial roles in many cellular processes including development, cell proliferation, differentiation and cell survival. Possible redundancy between the two isoforms has always been an issue since most biochemical tools do not differentiate between the two proteins. Thus, much effort has been made during the last decades to characterize the...

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Identifiers

PMID: 23690951
DOI: 10.1371/journal.pone.0062756
PMCID: PMC3653893

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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