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Article

Involvement of the PKC family in regulation of early development

23 Sept 2009

Abstract excerpt

Protein kinase C (PKC) isotypes have been implicated in a number of key steps during gametogenesis, fertilization, and early development. The 11-member family of PKC isotypes, many with different cofactor requirements for activation, can provide for differential activation of the specific kinases. In addition the enrichment of particular PKC isotypes to unique locations within gametes, zygotes, and early embryos...

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PMID: 19777543
DOI: 10.1002/mrd.21112

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