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Article

Programmed death-1 shapes memory phenotype CD8 T cell subsets in a cell-intrinsic manner.

Journal of immunology (Baltimore, Md. : 1950) - 15 Jun 2013

Charlton Joanna J, Chatzidakis Ioannis, Tsoukatou Debbie, Boumpas Dimitrios T, Garinis George A, Mamalaki Clio

Abstract excerpt

Memory phenotype T cells, found in unimmunized mice, display phenotypic and functional traits of memory cells and provide essential protection against infections, playing a role in both innate and adaptive immune responses. Mechanisms governing homeostasis of these memory phenotype T cells remain ill-defined. In this study, we reveal a crucial role of the negative costimulator programmed death-1 (PD-1) in...

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Identifiers

PMID: 23686498
DOI: 10.4049/jimmunol.1201617

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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