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Article

Gene expression characteristics of CD28null memory phenotype CD8+ T cells and its implication in T-cell aging.

Immunological reviews - 1 Jun 2005

Fann Monchou, Chiu Wai Kan, Wood William H, Levine Bruce L, Becker Kevin G, Weng Nan-Ping

Abstract excerpt

Accumulation of CD28(null)CD8(+) T cells is considered as one of the hallmarks of aging in the human immune system. However, the precise changes of CD28(null)CD8(+) T cells, compared to those of the precursor CD28(+)CD8(+) memory T cells, have not been determined. In this study, we present an analysis of the global gene expression profiles of CD28(+) and CD28(null) memory phenotype CD8(+) T cells. These two...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 15882354
DOI: 10.1111/j.0105-2896.2005.00262.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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