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Article

Tissue repair through cell competition and compensatory cellular hypertrophy in postmitotic epithelia.

Developmental cell - 28 May 2013

Tamori Yoichiro, Deng Wu-Min

Abstract excerpt

In multicellular organisms, tissue integrity and organ size are maintained through removal of aberrant or damaged cells and compensatory proliferation. Little is known, however, about this homeostasis system in postmitotic tissues, where tissue-intrinsic genetic programs constrain cell division and new cells no longer arise from stem cells. Here we show that, in postmitotic Drosophila follicular epithelia,...

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Identifiers

PMID: 23685249
DOI: 10.1016/j.devcel.2013.04.013
PMCID: PMC3891806

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