Article

Non-autonomous insulin signaling delays mitotic progression in <i>C. elegans</i> germline stem and progenitor cells

2024-07-02

Abstract excerpt

Stem and progenitor cell mitosis is essential for tissue development and homeostasis. How these cells ensure proper chromosome segregation, and thereby maintain mitotic fidelity, in the complex physiological environment of a living animal is poorly understood. Here we use in situ live-cell imaging of C. elegans germline stem and progenitor cells (GSPCs) to ask how the signaling environment influences stem and pr...

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Literature Corpus work: 1acf57f9-e5d0-53f9-9648-fdc4b98536df
DOI: 10.1101/2024.06.28.601188

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