Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The regulated elimination of transit-amplifying cells preserves tissue homeostasis during protein starvation in <i>Drosophila</i> testis

12 May 2015

Abstract excerpt

How tissues adapt to varying nutrient conditions is of fundamental importance for robust tissue homeostasis throughout the life of an organism, but the underlying mechanisms are poorly understood. Here, we show that Drosophila testis responds to protein starvation by eliminating transit-amplifying spermatogonia (SG) while maintaining a reduced pool of actively proliferating germline stem cells (GSCs). During...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetics, Aging, and Longevity in Model Organisms
Share to Invertebrate Immune Response Mechanisms
Share to Sperm and Testicular Function

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 25968311
DOI: 10.1242/dev.122663

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The regulated elimination of transit-amplifying cells preserves tissue homeostasis during protein starvation in <i>Drosophila</i> testisPMID 25968311Read ↗

Cell cycle exit and stem cell differentiation are coupled through regulation of mitochondrial activity in the Drosophila testisSemantic proximity Read ↗

Tissue repair through cell competition and compensatory cellular hypertrophy in postmitotic epithelia.Semantic proximity Read ↗

Autophagy slows the aging of Germline stem cells in <i>Drosophila</i> through modulation of E-cadherinSemantic proximity Read ↗

Stem cells commit to differentiation following multiple induction events in the Drosophila testisSemantic proximity Read ↗

Alternative somatic and germline gene-regulatory strategies during starvation-induced developmental arrestSemantic proximity Read ↗

Dedifferentiating Spermatogonia Outcompete Somatic Stem Cells for Niche Occupancy in the Drosophila TestisSemantic proximity Read ↗

Regeneration of Male Germline Stem Cells by Spermatogonial Dedifferentiation in VivoSemantic proximity Read ↗

TRiC activates the unfolded protein response and protects starved stem cells by modulating energy and lipid metabolism during planarian regenerationSemantic proximity Read ↗

A window of cell cycle plasticity enables imperfect regeneration of an adult postmitotic organ in <i>Drosophila</i>Semantic proximity Read ↗

Starve-Feed Cycles Direct Quiescence to Proliferation Transitions in <i>Drosophila</i> Follicle Stem Cells via Transcriptional RegulationSemantic proximity Read ↗

Daughterless coordinates somatic cell proliferation, differentiation and germline cyst survival during follicle formation in Drosophila.Semantic proximity Read ↗

Autophagy is dispensable in germline stem cells but is required in the cap cells for their maintenance in the Drosophila ovarian nicheSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.