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Article

Cancer-associated fibroblasts induce sorafenib resistance of hepatocellular carcinoma cells through CXCL12/FOLR1

2023-08-23

Abstract excerpt

<h4>Background: </h4> Due to the high drug resistance of hepatocellular carcinoma (HCC), Sorafenib has limited efficacy in the treatment of advanced HCC. Cancer-associated fibroblasts (CAFs) play an important regulatory role in the induction of chemo-resistance. This study aimed to clarify the mechanism underlying CAF-mediated resistance to sorafenib in HCC. <h4>Methods: </h4>: Immunohistochemistry and immunofluo...

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Literature Corpus work
88794111-073b-5f43-bbd6-750a99a40cd5
DOI
10.21203/rs.3.rs-3152222/v1
Open publication

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Cancer-associated fibroblasts induce sorafenib resistance of hepatocellular carcinoma cells through CXCL12/FOLR1DOI 10.21203/rs.3.rs-3152222/v1
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