Article
CACNA1C, schizophrenia and major depressive disorder in the Han Chinese population.
The British journal of psychiatry : the journal of mental science - 1 Jan 2014
He Kuanjun, An Zhiguo, Wang Qingzhong, Li Tao, Li Zhiqiang, Chen Jianhua, Li Wenjin, Wang Ti, Ji Jue, Feng Guoyin, Lin He, Yi Qizhong, Shi Yongyong
Abstract excerpt
BACKGROUND: Common psychiatric disorders are highly heritable, indicating that genetic factors play an important role in their aetiology. The CACNA1C gene, which codes for subunit alpha-1C of the Cav1.2 voltage-dependent L-type calcium channel, has been consistently found to be the shared risk gene for several kinds of mental disorder. AIMS: To investigate whether CACNA1C is a susceptibility gene for...
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