New breast cancer risk variant discovered at 10q25 in East Asian women.

doi:10.1158/1055-9965.EPI-12-1393

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New breast cancer risk variant discovered at 10q25 in East Asian women.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Jul 2013

Shi Jiajun, Sung Hyuna, Zhang Ben, Lu Wei, Choi Ji-Yeob, Xiang Yong-Bing, Kim Mi Kyung, Iwasaki Motoki, Long Jirong, Ji Bu-Tian, Park Sue K, Zheng Ying, Tsugane Shoichiro, Yoo Keun-Young, Wang Wenjing, Noh Dong-Young, Han Wonshik, Kim Sung-Won, Lee Min Hyuk, Lee Jong Won, Lee Jong-Young, Shen Chen-Yang, Matsuo Keitaro, Ahn Sei-Hyun, Gao Yu-Tang, Shu Xiao Ou, Cai Qiuyin, Kang Daehee, Zheng Wei

Abstract excerpt

BACKGROUND: Recently, 41 new genetic susceptibility loci for breast cancer risk were identified in a genome-wide association study (GWAS) conducted in European descendants. Most of these risk variants have not been directly replicated in Asian populations. METHODS: We evaluated nine of those nonreplication loci in East Asians to identify new risk variants for breast cancer in these regions. First, we analyzed...

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PMID: 23677579
DOI: 10.1158/1055-9965.EPI-12-1393
PMCID: PMC3720126

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