Article
Genome-wide association study identifies breast cancer risk variant at 10q21.2: results from the Asia Breast Cancer Consortium.
Human molecular genetics - 15 Dec 2011
Cai Qiuyin, Long Jirong, Lu Wei, Qu Shimian, Wen Wanqing, Kang Daehee, Lee Ji-Young, Chen Kexin, Shen Hongbing, Shen Chen-Yang, Sung Hyuna, Matsuo Keitaro, Haiman Christopher A, Khoo Ui Soon, Ren Zefang, Iwasaki Motoki, Gu Kai, Xiang Yong-Bing, Choi Ji-Yeob, Park Sue K, Zhang Lina, Hu Zhibin, Wu Pei-Ei, Noh Dong-Young, Tajima Kazuo, Henderson Brian E, Chan Kelvin Y K, Su Fengxi, Kasuga Yoshio, Wang Wenjing, Cheng Jia-Rong, Yoo Keun-Young, Lee Jong-Young, Zheng Hong, Liu Yao, Shieh Ya-Lan, Kim Sung-Won, Lee Jong Won, Iwata Hiroji, Le Marchand Loic, Chan Sum Yin, Xie Xiaoming, Tsugane Shoichiro, Lee Min Hyuk, Wang Shenming, Li Guoliang, Levy Shawn, Huang Bo, Shi Jiajun, Delahanty Ryan, Zheng Ying, Li Chun, Gao Yu-Tang, Shu Xiao-Ou, Zheng Wei
Abstract excerpt
Although approximately 20 common genetic susceptibility loci have been identified for breast cancer risk through genome-wide association studies (GWASs), genetic risk variants reported to date explain only a small fraction of heritability for this common cancer. We conducted a four-stage GWAS including 17 153 cases and 16 943 controls among East-Asian women to search for new genetic risk factors for breast...
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