Article
The stochastic silencing phenotype of Arabidopsis morc6 mutants reveals a role in efficient RNA-directed DNA methylation.
The Plant journal : for cell and molecular biology - 1 Sept 2013
Brabbs Thomas R, He Zhesi, Hogg Karen, Kamenski Andrei, Li Yi, Paszkiewicz Konrad H, Moore Karen A, O'Toole Peter, Graham Ian A, Jones Louise
Abstract excerpt
The RNA-directed DNA methylation (RdDM) pathway is of central importance to the initiation and maintenance of transcriptional gene silencing in plants. DNA methylation is directed to target sequences by a mechanism that involves production of small RNAs by RNA polymerase IV and long non-coding RNAs by RNA polymerase V. DNA methylation then leads to recruitment of histone-modifying enzymes, followed by...
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