Article
Arabidopsis AtMORC4 and AtMORC7 Form Nuclear Bodies and Repress a Large Number of Protein-Coding Genes.
PLoS genetics - 1 May 2016
Harris C Jake, Husmann Dylan, Liu Wanlu, Kasmi Farid El, Wang Haifeng, Papikian Ashot, Pastor William A, Moissiard Guillaume, Vashisht Ajay A, Dangl Jeffery L, Wohlschlegel James A, Jacobsen Steven E
Abstract excerpt
The MORC family of GHKL ATPases are an enigmatic class of proteins with diverse chromatin related functions. In Arabidopsis, AtMORC1, AtMORC2, and AtMORC6 act together in heterodimeric complexes to mediate transcriptional silencing of methylated DNA elements. Here, we studied Arabidopsis AtMORC4 and AtMORC7. We found that, in contrast to AtMORC1,2,6, they act to suppress a wide set of non-methylated...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
