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Article

Overexpression of EGFR in head and neck squamous cell carcinoma is associated with inactivation of SH3GL2 and CDC25A genes.

PloS one - 1 Jan 2013

Maiti Guru Prasad, Mondal Pinaki, Mukherjee Nupur, Ghosh Amlan, Ghosh Susmita, Dey Sanjib, Chakrabarty Jayanta, Roy Anup, Biswas Jaydip, Roychoudhury Susanta, Panda Chinmay Kumar

Abstract excerpt

The aim of this study is to understand the mechanism of EGFR overexpression in head and neck squamous cell carcinoma (HNSCC). For this reason, expression/mutation of EGFR were analyzed in 30 dysplastic head and neck lesions and 148 HNSCC samples of Indian patients along with 3 HNSCC cell lines. I...

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Share to Adaptor Proteins, Signal Transducing
Share to Carcinoma, Squamous Cell

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to cdc25 Phosphatases

Share to Gene Amplification

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Share to Head and Neck Neoplasms

Share to Papillomaviridae

Share to Squamous Cell Carcinoma of Head and Neck

Source

Open in PubMed Open full text

Identifiers

PMID: 23675485
DOI: 10.1371/journal.pone.0063440
PMCID: PMC3651136

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23675485-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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