Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of molecular targets in head and neck squamous cell carcinomas based on genome-wide gene expression profiling

1 Dec 2007

Abstract excerpt

DNA amplifications activate oncogenes and are hallmarks of nearly all advanced cancers including head and neck squamous cell carcinoma (HNSCC). Some oncogenes show both DNA copy number gain and mRNA overexpression. Chromosomal comparative genomic hybridization and oligonucleotide microarrays were used to examine 8 HNSCC cell lines and a plot of gene expression levels relative to their position on the chromosome...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related gene regulation
Share to Cholangiocarcinoma and Gallbladder Cancer Studies
Share to RNA modifications and cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 17982635
DOI: 10.3892/or.18.6.1489

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of molecular targets in head and neck squamous cell carcinomas based on genome-wide gene expression profilingPMID 17982635Read ↗

Homeobox B7 is a Newly Hypothesized Oncogene Promoting Tumorigenesis in Head and Neck Squamous Cell CarcinomaSemantic proximity Read ↗

Amplification of the EGFR and CCND1 Are Coordinated and Play Important Roles in the Progression of Oral Squamous Cell CarcinomasSemantic proximity Read ↗

Identification of upregulated genes in oral squamous cell carcinomasSemantic proximity Read ↗

Molecular profiling of head and neck tumors.Semantic proximity Read ↗

Genomic and Transcriptomic Characterization Links Cell Lines with Aggressive Head and Neck CancersSemantic proximity Read ↗

Global gene expression profiles of human head and neck squamous carcinoma cell linesSemantic proximity Read ↗

Aberrant Epigenetic Regulation in Head and Neck Cancer Due to Distinct EZH2 Overexpression and DNA Hypermethylation<strong> </strong>Semantic proximity Read ↗

Differential expression profiling of head and neck squamous cell carcinoma (HNSCC)Semantic proximity Read ↗

Prognostic Significance of theBIRC2-BIRC3Gene Signature in Head and Neck Squamous Cell CarcinomaSemantic proximity Read ↗

Gene Expression Signatures for Head and Neck Cancer Patient Stratification: Are Results Ready for Clinical Application?Semantic proximity Read ↗

Copy number alterations identify a smoking-associated expression signature predictive of poor outcome in head and neck squamous cell carcinoma.Semantic proximity Read ↗

Targeting histone deacetylases in head and neck squamous cell carcinoma: molecular mechanisms and therapeutic targetsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.