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Article

A dose-response analysis of ethylnitrosourea-induced recessive specific-locus mutations in treated spermatogonia of the mouse.

Mutation research - 1 Jul 1990

Favor J, Sund M, Neuhäuser-Klaus A, Ehling U H

Abstract excerpt

A dose-response analysis was carried out with 2 independent data sets available for ethylnitrosourea-induced specific-locus mutations in spermatogonia of the mouse. It was assumed that the occurrence of mutation is binomially distributed and maximum-likelihood procedures were employed to determine the appropriateness of 4 alternative models, Linear, Linear-Quadratic, Power, and Threshold, in describing the...

Topics

Animals
Crosses, Genetic
DNA Repair
Dose-Response Relationship, Drug
Ethylnitrosourea
Female
Genes, Recessive
Male
Mice
Mice, Mutant Strains
Models, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Models, Statistical

Mutation

Spermatogonia

Spermatozoa

Source

Identifiers

PMID: 2366775
DOI: 10.1016/0027-5107(90)90175-4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2366775-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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A dose-response analysis of ethylnitrosourea-induced recessive specific-locus mutations in treated spermatogonia of the mouse.PMID 2366775Read ↗

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The effect of the interval between dose applications on the observed specific-locus mutation rate in the mouse following fractionated treatments of spermatogonia with ethylnitrosourea.Semantic proximity Read ↗

The frequency of dominant cataract and recessive specific-locus mutations and mutation mosaics in F1 mice derived from post-spermatogonial treatment with ethylnitrosourea.Semantic proximity Read ↗

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