Article
Distinct functional and temporal requirements for zebrafish Hdac1 during neural crest-derived craniofacial and peripheral neuron development.
PloS one - 1 Jan 2013
Ignatius Myron S, Unal Eroglu Arife, Malireddy Smitha, Gallagher Glen, Nambiar Roopa M, Henion Paul D
Abstract excerpt
The regulation of gene expression is accomplished by both genetic and epigenetic means and is required for the precise control of the development of the neural crest. In hdac1(b382) mutants, craniofacial cartilage development is defective in two distinct ways. First, fewer hoxb3a, dlx2 and dlx3-expressing posterior branchial arch precursors are specified and many of those that are consequently undergo apoptosis....
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