Article
Histone deacetylase 1 regulates retinal neurogenesis in zebrafish by suppressing Wnt and Notch signaling pathways.
Development (Cambridge, England) - 1 Jul 2005
Yamaguchi Masahiro, Tonou-Fujimori Noriko, Komori Atsuko, Maeda Ryu, Nojima Yasuhiro, Li Haichang, Okamoto Hitoshi, Masai Ichiro
Abstract excerpt
In the developing vertebrate retina, progenitor cells initially proliferate but begin to produce postmitotic neurons when neuronal differentiation occurs. However, the mechanism that determines whether retinal progenitor cells continue to proliferate or exit from the cell cycle and differentiate...
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