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Article

Identification of CAD candidate genes in GWAS loci and their expression in vascular cells.

Journal of lipid research - 1 Jul 2013

Erbilgin Ayca, Civelek Mete, Romanoski Casey E, Pan Calvin, Hagopian Raffi, Berliner Judith A, Lusis Aldons J

Abstract excerpt

Recent genome-wide association studies (GWAS) have identified 35 loci that significantly associate with coronary artery disease (CAD) susceptibility. The majority of the genes represented in these loci have not previously been studied in the context of atherosclerosis. To characterize the roles of these candidate genes in the vessel wall, we determined their expression levels in endothelial, smooth muscle, and...

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Source

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Identifiers

PMID: 23667179
DOI: 10.1194/jlr.M037085
PMCID: PMC3679391

Genes

CAD
GALNT4
ICAM1
MAPKAPK5
SNF8
SRR
TCTN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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