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Article

Cell phenotype phase separation in epithelial-mesenchymal transition-mediated collective cell migration.

Acta biomaterialia - 1 Sept 2026

Sun Weihao, Xue Rui, Pang Ruiyang, Duan Xiaocen, Xu Hongwei, Xiong Chunyang, Huang Jianyong

Abstract excerpt

Collective cell migration plays a critically regulatory role in both physiological and pathological processes, e.g., embryonic development, wound healing, cancer progression and metastasis. Nevertheless, spatiotemporal progression of epithelial and mesenchymal cell migration remains poorly understood. Here, we report an epithelial-mesenchymal transition (EMT)-modulated cell phenotype phase separation (CPPS)...

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PMID: 42463070
DOI: 10.1016/j.actbio.2026.07.029

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