Article
Toll-like receptor 1 gene polymorphisms in childhood IgA nephropathy: a case-control study in the Korean population.
International journal of immunogenetics - 1 Apr 2011
Lee J S, Park H-K, Suh J-S, Hahn W-H, Kang S W, Park H J, Kim M J, Chung J-H, Cho B-S
Abstract excerpt
Toll-like receptors (TLRs) are innate immune mediators that stimulate nuclear factor kappa B and the inflammatory cytokines. TLR1 is expressed in renal tubular epithelial cells when the kidney is injured, but the role of TLR1 gene in glomerulonephritis has not been clearly elucidated. We aimed to investigate the association of TLR1 polymorphisms with immunoglobulin A nephropathy (IgAN) in children. One hundred...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
