Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic variants of MCP-1 and CCR2 genes and IgA nephropathy risk.

Oncotarget - 22 Nov 2016

Gao Jie, Liu Xinghan, Wei Linting, Niu Dan, Wei Jiali, Wang Li, Ge Heng, Wang Meng, Yu Qiaoling, Jin Tianbo, Tian Tian, Dai Zhijun, Fu Rongguo

Abstract excerpt

Monocyte chemoattractant protein-1 (MCP-1) and its receptor CCR2 stimulate inflammation response by activating and recruiting monocytes/macrophages. MCP-1 and CCR2 polymorphisms were reported to be associated with various diseases. To explore the relationship between MCP-1 and CCR2 polymorphisms and IgA nephropathy (IgAN), we conducted this case-control study by enrolling 351 IgAN patients and 310 health...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Case-Control Studies
Share to Chemokine CCL2

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to CCR2 gene

Share to Genetic Predisposition to Disease

Share to Genetic Variation

Share to Glomerulonephritis, IGA

Share to Receptors, CCR2

Share to Risk Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 27788494
DOI: 10.18632/oncotarget.12847
PMCID: PMC5363634

Genes

CCR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic variants of MCP-1 and CCR2 genes and IgA nephropathy risk.PMID 27788494Read ↗

Association of Immune and Inflammatory Gene Polymorphism With the Risk of IgA Nephropathy: A Systematic Review and Meta-Analysis of 45 Studies.Semantic proximity Read ↗

A genome-wide association study in Han Chinese identifies multiple susceptibility loci for IgA nephropathy.Semantic proximity Read ↗

TLR1 polymorphism rs4833095 as a risk factor for IgA nephropathy in a Chinese Han population: A case-control study.Semantic proximity Read ↗

Genetic variants of the MIR31HG gene are related to a risk of IgA nephropathy.Semantic proximity Read ↗

Monocyte chemoattractant protein-1 -2518G/A gene polymorphism and the risk of nephropathy in type 2 diabetes mellitus among Asians: a meta-analysis.Semantic proximity Read ↗

Polymorphisms of CXCL8 and its receptor CXCR2 contribute to the development and progression of childhood IgA nephropathy.Semantic proximity Read ↗

Association of Interleukin-10 Polymorphisms (rs1800872, rs1800871, and rs1800896) with Predisposition to IgA Nephropathy in a Chinese Han Population: A Case-Control Study.Semantic proximity Read ↗

Association between the MCP-1 -2518 A > G (rs1024611) polymorphism and susceptibility to type 2 diabetes mellitus and diabetic nephropathy: a meta-analysis.Semantic proximity Read ↗

Genetic Variants in MIR3142HG Contribute to the Predisposition of IgA Nephropathy in a Chinese Han Population.Semantic proximity Read ↗

Association between CCDC132, FDX1 and TNFSF13 gene polymorphisms and the risk of IgA nephropathy.Semantic proximity Read ↗

Replication of genome-wide association study identified seven susceptibility genes, affirming the effect of rs2856717 on renal function and poor outcome of IgA nephropathy.Semantic proximity Read ↗

What Genetics Tells Us About the Pathogenesis of IgA Nephropathy: The Role of Immune Factors and InfectionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.