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Article

IL-25 enhances HSV-1 replication by inhibiting filaggrin expression, and acts synergistically with Th2 cytokines to enhance HSV-1 replication.

The Journal of investigative dermatology - 1 Dec 2013

Kim Byung Eui, Bin Lianghua, Ye Young-Min, Ramamoorthy Preveen, Leung Donald Y M

Abstract excerpt

Atopic dermatitis (AD) is characterized by epidermal barrier defects and recurrent microbial skin infections. AD patients with a history of eczema herpeticum (ADEH+) have more severe skin disease and more highly T helper type 2 (Th2)-polarized immune responses as compared with uncomplicated AD (ADEH-). However, the mechanisms linking epidermal barrier defects and viral skin infection are not well understood....

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Identifiers

PMID: 23657503
DOI: 10.1038/jid.2013.223
PMCID: PMC3785566

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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