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Article

Isometric contraction of Dupuytren's myofibroblasts is inhibited by blocking intercellular junctions.

The Journal of investigative dermatology - 1 Dec 2013

Verhoekx Jennifer S N, Verjee Liaquat S, Izadi David, Chan James K K, Nicolaidou Vicky, Davidson Dominique, Midwood Kim S, Nanchahal Jagdeep

Abstract excerpt

Myofibroblasts (MFs) are responsible for both physiological wound and scar contraction. However, it is not known whether these cells act individually to contract the surrounding matrix or whether they behave in a coordinated manner. Therefore, we studied intercellular junctions of primary human MFs derived from patients with Dupuytren's disease, a fibrotic disorder of the dermis and subdermal tissues of the palm....

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PMID: 23652794
DOI: 10.1038/jid.2013.219

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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