Article
Pharmacogenetic determinants of outcome in acute lymphoblastic leukaemia.
British journal of haematology - 1 May 2004
Aplenc Richard, Lange Beverly
Abstract excerpt
Present day paediatric co-operative group acute lymphoblastic leukaemia (ALL) protocols cure approximately 80% of patients, a result achieved largely through the use of risk-stratified therapies that employ multiple chemotherapy agents. These risk-based therapies utilize host and leukaemia traits to select the most appropriate therapy. However, these risk-stratified approaches predict therapy response imperfectly...
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