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Article

A role for synaptic zinc in ProSAP/Shank PSD scaffold malformation in autism spectrum disorders.

Developmental neurobiology - 1 Feb 2014

Grabrucker Andreas M

Abstract excerpt

The establishment and maintenance of synaptic contacts as well as synaptic plasticity are crucial factors for normal brain function. The functional properties of a synapse are largely dependent on the molecular setup of synaptic proteins. Multidomain proteins of the ProSAP/Shank family act as major organizing scaffolding elements of the postsynaptic density (PSD). Interestingly, ProSAP/Shank proteins at...

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Identifiers

PMID: 23650259
DOI: 10.1002/dneu.22089
PMCID: PMC4272576

Genes

PSD

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