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Article

Role of Nrf2 in cancer photodynamic therapy: regulation of human ABC transporter ABCG2.

Journal of pharmaceutical sciences - 1 Sept 2013

Ishikawa Toshihisa, Kajimoto Yoshinaga, Sun Wei, Nakagawa Hiroshi, Inoue Yutaka, Ikegami Yoji, Miyatake Shin-Ichi, Kuroiwa Toshihiko

Abstract excerpt

Photodynamic therapy (PDT) is a recently developed anticancer treatment that utilizes the generation of singlet oxygen and other reactive oxygen species in cancer tissue. In response to oxidative stress, NF-E2-related transcription factor (Nrf2) encoded by the NFE2L2 gene plays a key role in transcriptional upregulation of many target genes, including those for metabolizing enzymes and transporters essential for...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23650051
DOI: 10.1002/jps.23563

Genes

ABCG2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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