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Article

Nrf2 pathway regulates multidrug-resistance-associated protein 1 in small cell lung cancer.

PloS one - 1 Jan 2013

Ji Lili, Li Hui, Gao Pan, Shang Guoguo, Zhang Donna D, Zhang Nong, Jiang Tao

Abstract excerpt

Although multidrug-resistance-associated protein-1 (MRP1) is a major contributor to multi-drug resistance (MDR), the regulatory mechanism of Mrp1 still remains unclear. Nrf2 is a transcription factor that regulates cellular defense response through antioxidant response elements (AREs) in normal t...

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Identifiers

PMID: 23667609
DOI: 10.1371/journal.pone.0063404
PMCID: PMC3646742

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23667609-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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