IL2/IL21 region polymorphism influences response to rituximab in systemic lupus erythematosus patients.

doi:10.1007/s11033-013-2583-6

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Article

IL2/IL21 region polymorphism influences response to rituximab in systemic lupus erythematosus patients.

Molecular biology reports - 1 Aug 2013

Márquez Ana, Dávila-Fajardo Cristina Lucía, Robledo Gema, Rubio José Luis Callejas, de Ramón Garrido Enrique, García-Hernández Francisco J, González-León Rocío, Ríos-Fernández Raquel, Barrera José Cabeza, González-Escribano Ma Francisca, García Ma Teresa Camps, Palma Ma Jesús Castillo, del Mar Ayala Ma, Ortego-Centeno Norberto, Martín Javier

Abstract excerpt

To determine whether the IL2/IL21 region, a general autoimmunity locus, contributes to the observed variation in response to rituximab in patients with systemic lupus erythematosus as well as to analyze its influence in a cohort including other autoimmune diseases. rs6822844 G/T polymorphism at the IL2-IL21 region was analyzed by TaqMan assay in 84 systemic lupus erythematosus (SLE) and 60 different systemic...

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PMID: 23645042
DOI: 10.1007/s11033-013-2583-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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