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Article

Association between -174 interleukin-6 gene polymorphism and biological response to rituximab in several systemic autoimmune diseases.

DNA and cell biology - 1 Sept 2012

Robledo Gema, Dávila-Fajardo Cristina Lucía, Márquez Ana, Ortego-Centeno Norberto, Callejas Rubio José Luis, de Ramón Garrido Enrique, Sánchez-Román Julio, García-Hernández Francisco J, Ríos-Fernández Raquel, González-Escribano Maria Francisca, Camps García Maria Teresa, Castillo Palma Maria Jesús, Ayala Maria Del Mar, Martín Javier

Abstract excerpt

Rituximab has become a pivotal treatment for systemic autoimmune diseases. The aim of this study was to determine whether the genetic variant -174 IL-6 contributes to differences in the response to rituximab in patients with systemic autoimmune diseases, including systemic lupus erythematosus (SLE), inflammatory myopathies, anti-neutrophil cytoplasmic antibody-mediated vasculitis, systemic sclerosis, Sjöegren's...

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Share to Antibodies, Monoclonal, Murine-Derived

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

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Identifiers

PMID: 22734797
DOI: 10.1089/dna.2012.1684

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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