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Article

Chromatin remodeling of human subtelomeres and TERRA promoters upon cellular senescence: commonalities and differences between chromosomes.

Epigenetics - 1 May 2013

Thijssen Peter E, Tobi Elmar W, Balog Judit, Schouten Suzanne G, Kremer Dennis, El Bouazzaoui Fatiha, Henneman Peter, Putter Hein, Eline Slagboom P, Heijmans Bastiaan T, van der Maarel Silvère M

Abstract excerpt

Subtelomeres are patchworks of evolutionary conserved sequence blocks and harbor the transcriptional start sites for telomere repeat containing RNAs (TERRA). Recent studies suggest that the interplay between telomeres and subtelomeric chromatin is required for maintaining telomere function. To further characterize chromatin remodeling of subtelomeres in relation to telomere shortening and cellular senescence, we...

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Identifiers

PMID: 23644601
DOI: 10.4161/epi.24450
PMCID: PMC3741221

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CTCF
VIPR2

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