Article
The Drosophila gene tailless is expressed at the embryonic termini and is a member of the steroid receptor superfamily.
Cell - 13 Jul 1990
Pignoni F, Baldarelli R M, Steingrímsson E, Diaz R J, Patapoutian A, Merriam J R, Lengyel J A
Abstract excerpt
The zygotically active tailless (tll) gene plays a key role in the establishment of nonmetameric domains at the anterior and posterior poles of the Drosophila embryo. We have cloned the tll gene and show that it encodes a protein with striking similarity to steroid hormone receptors in both the DNA binding "finger" and ligand binding domains. tll RNA is initially expressed in embryos in two mirror-image...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Cloning, Molecular
- Drosophila
- Embryo, Nonmammalian
- Gene Expression
- Molecular Sequence Data
- Multigene Family
- Mutation
- Receptors, Steroid