Article
The homeobox gene Distal-less induces ventral appendage development in Drosophila.
Genes & development - 1 Sept 1997
Gorfinkiel N, Morata G, Guerrero I
Abstract excerpt
This study investigates the role of the homeobox gene Distal-less (Dll) in the development of the legs, antennae, and wings of Drosophila. Lack of Dll function causes a change in the identity of ventral appendage cells (legs and antennae) that often results in the loss of the appendage. Ectopic Dll expression in the proximal region of ventral appendages induces nonautonomous duplication of legs and antennae by...
Topics
- Animals
- Animals, Genetically Modified
- Drosophila
- Extremities
- Female
- Gene Expression Regulation, Developmental
- Genes, Homeobox
- Genes, Insect
- Genes, Reporter
- Male
- Phenotype
- Sense Organs